When it comes to weight loss supplements, there is no shortage of options to choose from. Between fat burners, appetite suppressants, metabolism boosters, and over-the-counter diet pills, finding the right product can feel like an overwhelming task.
But don’t worry, we got you covered!
We’ve reviewed over 25 of the top-rated weight loss supplements on the market to see which ones are the most effective for shedding off the extra weight. We analyzed each product based on its ingredients, side effects, price, dosage, customer reviews, and product guarantees.
If you’re struggling to lose weight, burn body fat, or you just want to look the best you have in years, here are the best weight loss pills on the market.
Top 5 Best Weight Loss Supplements of 2021
#1) Leanbean: Best Weight Loss Pills For Women
LeanBean is our top pick for the best weight loss pill for women. This product’s cutting-edge formula provides the energy women need to look and feel their best. It contains metabolism-boosting ingredients that kick the body into a state of thermogenesis.
The secret ingredient is glucomannan, a water-soluble dietary fiber derived from konjac root. Each weight loss pill contains three grams of glucomannan, an amount determined optimal via clinical research in the European Union. The substance makes women feel full between meals so that they don’t overeat.
Other ingredients in Leanbean include:
Leanbean does more than help women lose weight. The energy-boosting pill can reduce tiredness and fatigue, allowing individuals to conquer the busiest social and professional schedules. The unique formula can even improve concentration.
Ultimate Life Ltd., the company behind Leanbean, recommends taking six pills per day, beginning with two tablets at breakfast, then repeating at lunch and dinner, all with a glass of water. Spreading out the pill consumption enables the optimal results, thanks to the perpetual fat-burning effect.
Leanbean provides a weight loss solution tailor-made for women. The clinically-tested formula doesn’t have aggressive stimulants or side effects associated with male weight loss pills. A daily dose of Leanbean can help women achieve that firmer, fitter body in no time.
#2) Instant Knockout: Best Weight Loss Pill For Men
Instant Knockout is our top choice for the best fat burner for men. Originally designed to help pro boxers and MMA fighters get shredded before an upcoming fight, Instant Knockout is now available to the general public. This product is based on the latest scientific research and contains 10 powerful fat burning ingredients.
Here is what Instant Knockout can do for you:
Our favorite thing about Instant Knockout is the high-quality ingredients inside each pill. Unlike other weight loss pills, there is no cost-cutting, no pointless ingredients, and no proprietary formulas that hide the exact dosage of each ingredient. Just powerful fat burning ingredients that are dosed right and backed by the latest scientific research.
Here is the ingredient list inside of Instant Knockout:
A single bottle of Instant Knockout contains 30 servings, enough for a 30-day supply. The recommended dosage is 1 capsule, 4 times per day. By taking four equal doses throughout the day, you’ll burn fat for a longer period of time than if you were to take all 4 capsules at once.
Instant Knockout is for any man that wants to lose stubborn fat. Whether you’re an athlete or just want to upgrade the “dad bod”, Instant Knockout can help you reach your goals fast.
#3) PhenQ: Best Weight Loss Supplement For Losing Over 30 Lbs
PhenQ is the top weight loss supplement for men or women needing to lose more than 30 lbs. Most weight loss pills take a singular approach to help you lose weight. PhenQ strays from the pack with a multi-pronged approach. The comprehensive formula has provided 190,000 customers with the fuel they needed to achieve their ideal body.
The PhenQ fat burner pill uses four different methods to help people lose weight:
The fact that it also enhances a person’s mood is a pleasant bonus.
PhenQ works for anyone in search of dramatic weight loss. Even a person looking to shed more than 30 pounds can benefit from this state-of-the-art pill. The dramatic effects have made PhenQ one of the most trusted weight loss options on the market.
Each pill contains a-Lacys Reset, a compound that can reduce fat and body weight while bolstering muscle mass. Trials show that a-Lacys Reset helps patients lose 7.24% of body fat and 3.44% of body weight. That’s on top of a 3.80% gain in muscle mass.
Other components in the PhenQ formula include:
Each bottle of PhenQ comes with 60 pills, enough for a one-month supply. The manufacturer recommends taking two tablets per day, one in the morning and one in the evening. Anyone that doesn’t see results can return their PhenQ, no questions asked.
The PhenQ fat burner comes with free shipping and a 60-day money-back guarantee. Users do not need a prescription to purchase PhenQ and can capitalize on discounted prices when they purchase in bulk. If you have any comments or questions, you can reach out to PhenQ’s customer service 24 hours a day, seven days a week.
#4) PhenGold: Top Rated Weight Loss Pill For Boosting Metabolism
PhenGold is the top fat burner supplement for boosting metabolism. Your metabolism plays a central role in weight regulation. Anyone that wants to increase fat-burning potential would benefit from a jump start in their metabolic rate. PhenGold offers precisely that in a weight loss pill.
PhenGold utilizes robust ingredients that naturally speed up metabolism. For instance, clinical research shows that L-theanine improves fat loss, while cayenne pepper increases daily caloric burn. Other ingredients in PhenGold include:
PhenGold comes with a laundry list of benefits for health-conscious consumers. The weight loss pill does not contain lactose, soy, or artificial ingredients. It also works for anyone on a vegetarian or vegan diet.
Each PhenGold bottle contains 90 capsules. Take three pills per day, spaced at even intervals. These weight loss pills contain all-natural ingredients and have minimal side effects.
The manufacturer, Swiss Research Labs Ltd., makes all PhenGold in the United States. It also offers a 100% money-back guarantee and 24-hour shipping. You can take advantage of discounts on their purchases by buying more than a 1-month supply.
#5) TrimTone: Top Weight Loss Pill For Appetite Suppression
TrimTone is the best-rated weight loss pill for appetite suppression. The weight loss pill utilizes thermogenesis, so the body goes into fat-burning overdrive. A single dose of TrimTone with water is all you need to start looking and feeling your best.
The supplement works for anyone on a busy schedule. Juggling work, children, dinner, and exercise can be exhausting, and the TrimTone manufacturer understands that. The straightforward capsule makes weight loss easier than ever.
TrimTone has an all-natural formula for long-lasting appetite suppression. That includes caffeine anhydrous, coffee beans, and green tea for an invigorating experience. The complete lineup of ingredients includes:
TrimTone contains a healthy dose of glucomannan to keep hunger pangs at bay. The dietary fiber decreases the desire to overeat during the day. Users don’t have to worry about raiding the pantry for sugar treats to satisfy late-night cravings, either.
This best-selling weight loss pill comes from Swiss Research Labs Limited. This company makes all its products in the United States and offers free delivery. Purchase TrimTone today, and take advantage of its money-back guarantee.
Natural Ingredients Found In Weight Loss Pills That Work
Green Tea Extract
Green tea is not only a healthy beverage but a beneficial weight loss supplement. Researchers have linked green tea extract to improved appetite suppression and fat burning. The copious amounts of caffeine also provide the energy you’ll need to make it through tough workouts.
Weight loss pills with green tea extract break down fat cells before moving them into the bloodstream. Green tea extract is an active stimulate for fat-burning hormones in the body, such as norepinephrine. The dietary supplement also has antioxidants that prevent the breakdown of norepinephrine, making it easier to get rid of fat deposits.
Green Coffee Bean Extract
A daily dose of green coffee bean extract might be what you need to achieve the body of your dreams. Coffee beans have a compound called chlorogenic acid that researchers believe can prevent aging, lower blood pressure, and burn fat. Note that roasting coffee beans may lower the concentration of chlorogenic acid.
Green coffee benefits from the presence of caffeine, which acts as an appetite suppressant. The substance interacts with your nervous system to quell hunger signals from the stomach to the brain. Caffeine also activates thermogenesis, enabling the body to generate heat and extract energy from food.
Garcinia Cambogia Extract
Garcinia cambogia extract comes from the Malabar tamarind and has become an increasingly popular dietary supplement. Researchers say that tropical fruit extract blocks the body from making adipose tissue and curbs appetite. Garcinia cambogia can even control cholesterol and blood sugar levels.
Garcinia cambogia extract can burn fat cells, thanks to the presence of hydroxycitric acid. The active ingredient prevents the enzyme citrate lyase from creating new adipose deposits. Hydroxycitric acid elevates serotonin levels, meaning that a single dose of garcinia cambogia acts as an appetite suppressant and mood booster.
Bitter orange (Citrus aurantium) has a long history of medicinal applications in China and Brazil. According to Andrew Weil, M.D., native tribes in the Amazon use bitter orange to treat constipation, nausea, and irregular bowel movements. The sour fruit induces a thermogenic response associated with weight loss.
However, bitter orange remains a controversial dietary supplement and may cause severe side effects. The fruit contains ephedra (ma-huang), a substance the U.S. Food and Drug Administration (FDA) banned in 2014. The National Center for Complementary and Alternative Medicine has linked ephedra to increased blood pressure, heart attacks, and strokes. While natural ingredients are often safer than synthetic ones, bitter orange proves that that’s not always the case.
Chromium is a mineral that may boost fat metabolism and help you burn calories faster. The safe and natural substance comes in several forms, with dietitians considering trivalent chromium an essential part of a healthy diet. Weight loss pill manufacturers use it in dietary supplements because of its effects on insulin.
Multiple studies show that chromium can improve blood sugar levels for people with diabetes. It also has potential as a weight-loss drug. A four-month study found that people who received a daily dose of the mineral lost 2.4 pounds more than those in the control group.
Raspberry ketone, also known as frambinone or rheosmin, is a chemical that gives red raspberries their aromatic quality. The compound exists in other berries and fruits, as well as in cosmetic products. Structurally, raspberry ketones mirror the molecular complexion of capsaicin and synephrine.
These structural similarities have led researchers to speculate about raspberry ketone’s ability to boost fat metabolism. Animal studies have already found that it can boost metabolism and the release of adiponectin, which regulates blood sugar levels. Raspberry ketones have the potential to help diabetics and people struggling with obesity.
L-carnitine is an amino acid linked to effective weight loss. The nutritional supplement transports fatty acids into the mitochondria, where the cell burns a high amount of fat for energy. You can find the amino acid in meat, fish, avocados, and beans.
The body naturally produces L-Carnitine, in addition to other forms of carnitine. For instance, Acetyl L-Carnitine regulates brain function, while Propionyl L-Carnitine improves circulation. Sports drink manufacturers often add L-carnitine L-tartrate to beverages to speed up mineral absorption and assist in muscle recovery.
Caffeine is one of several stimulants that can boost metabolism, along with chlorogenic acid, theophylline, and theobromine. It’s also the most widely consumed psychoactive substance globally, making it a popular choice for weight loss pills. Caffeine can help you lose weight because it blocks adenosine.
Blocking adenosine means that other neurons in your brain can fire, releasing neurotransmitters like norepinephrine and dopamine. These substances give you the jolt you need to feel alive and awake. Caffeine also increases your metabolic rate, making it easier to lose weight over the long-term. Some of the possible side effects of caffeine include an elevated heart rate, jitters, and insomnia. Caffeine is a common ingredient in many fat burners for its ability to help your body burn calories at a faster rate.
Conjugated Linoleic Acid
Conjugated linoleic acid (CLA) is a naturally occurring fatty acid in dairy and meat products. Cows, goats, and other mammals convert omega-6 fatty acids from their food into CLA through digestion. Researchers believe the substance contributes to weight loss in humans.
One trial gave mice conjugated linoleic acid for six weeks. The mice with CLA-supplemented-diets lost 70% more fat compared to those in the control group. A similar study on pigs discovered that CLA helped lower body fat.
Prescription Weight Loss Pills to Consider
Alli (60 mg of Orlistat) is an over-the-counter weight loss drug for people 18 years or older. Doctors recommend it for anyone looking to lose weight while on a low-fat diet. Individuals in need of a prescription weight loss drug can try its cousin, Xenical, which has the same active ingredient but at a higher dose.
Alli works by keeping the intestines from absorbing unwanted fat. The leftover fat from food leaves the body through the next bowel movement. This process limits how much dietary fat a person can store after a meal. The weight loss pill can also reduce side effects associated with visceral fat, including diabetes, stroke, hypertension, and heart disease.
Xenical (120 mg of Orlistat) is a higher, prescription-level dosage of the same drug as Alli. This prescription weight loss pill blocks enzymes that process fat in the bowels. These undigested fats pass through the body during subsequent bowel movements.
Xenical works well with a low-calorie diet and regular exercise. Users should lose weight within the first two weeks of taking the diet pills. Xenical may cause vitamin absorption complications, so doctors recommend taking a multivitamin once per day to offset side effects.
Contrave is the first and only prescription weight loss pill with FDA-approval. Nalpropion Pharmaceuticals created the drug to regulate the hunger and rewards mechanisms in the brain. The diet pills make it easier for users to control cravings and suppress their appetite.
Nalpriopion Pharmaceuticals gave more than 2,000 obese participants a daily dose of Contrave. The year-long trial found that 46% of people on Contrave lost at least 5% of their weight compared to 23% of people who took the placebo. If you want to optimize your weight loss results, be sure to take Contrave while on a low-fat diet.
Phentermine (Lomaira, Adipex-P) is a weight loss drug created in 1959. Doctors recommend using it for short-term weight loss along with topiramate, diet, and daily exercise. The pill functions like an amphetamine by suppressing the users’ appetites so that they don’t feel the urge to overeat.
Phentermine works best for obese people or those with weight-related medical conditions. The Food and Drug Administration (FDA) has classified it as a Schedule IV drug, meaning that people may abuse it. Possible side effects of phentermine include elevated heart rate, dry mouth, constipation, and nervousness.
Belviq (Lorcaserin) is a prescription weight loss drug, no longer on the market, that helps users control their appetite. This serotonin 2C receptor antagonist tricks the brain into thinking the stomach is full. Researchers suggest that a daily tablet of Belviq, along with a low-calorie diet and physical activity, is effective for weight loss.
Eisai Inc., the company behind Belviq, recently removed the diet pill from the market. The voluntary withdrawal came at the request of the FDA in February 2020. The agency determined that the risks outweigh the benefits following a long-term study of its cardiovascular side effects.
Factors To Consider When Buying Supplements For Weight Loss
What you put into your body matters. Make sure to read and understand all the ingredients in your weight loss pills before using them. The last thing you want is to consume banned substances, like sibutramine, fenfluramine, or ephedra, any of which may cause adverse side effects.
Look for the ingredients listed above under “Popular Ingredients” to find reliable weight loss products. Green tea, chromium, and caffeine are among the most popular active ingredients. These substances not only correlate with an increase in fat loss and weight loss potential but have extensive research behind them.
Every diet pill has a different dosage. Generic weight-loss drugs have lower concentrations of active ingredients than their prescription counterparts. The right diet pill for you will depend on your current health, body composition, allergies, and weight loss goals.
Make sure to use prescription and over-the-counter drugs as recommended. Some weight loss pills contain potentially addictive substances, like phentermine. Responsible long-term use will mitigate the chance of over-reliance and day-to-day side effects.
Safety / Side Effects
Your safety should be the top priority when choosing dietary supplements. Winding up in the hospital because of the medication defeats the purpose of weight loss. Read online reviews and talk with your primary physician before taking weight loss pills.
It’s normal to experience some side effects like nausea, dizziness, and headaches during your first few days of a new regimen. Your body needs time to adjust to the active ingredients. Get medical attention immediately if you have severe or long-lasting side effects.
Customer reviews are useful for seeing if dietary supplements for weight loss are worth your time and money. They highlight other people’s experiences, potential side effects, and weight loss results. While customer reviews shouldn’t make or break your purchase, they can make the decision easier, especially if you’re on the fence.
The most important review, though, comes from your doctor. Ask your primary care provider if the ingredients are safe or if they’ll interfere with any of your current medications. Doctors understand your medical and health history and have the right qualifications to give advice.
The best weight loss pills aren’t cheap. You should expect to pay at least $100 for a two-month supply of diet pills. While the upfront price might sting the wallet, remember that a dream body is priceless.
You can get more value out of your diet pills in two ways. First, buying in bulk allows you to save on long-term costs. For instance, a month’s worth of LeanBean costs $59, while a four-month supply costs $185, or $41.25 per month. Second, look for manufacturers that offer money-back guarantees, so you can have peace of mind knowing your weight-loss trial is risk-free.
How To Get The Best Results Out of Diet Supplements
Leading weight loss pills have the backing of scientific research and trials that have rigorously tested the drug’s performance before its release. If you want to achieve the ideal body results, start by following the instructions on the label. Adhering to manufacturer recommendations will reduce the chance of unpleasant side effects.
Diet pills are only part of the equation. You’re not going to achieve the perfect body if you don’t exercise regularly or eat a healthy diet. Incorporate strenuous physical activity and nutrient-rich foods into your daily regimen to get the desired results.
Types of Weight Loss Pills
Fat burners accelerate your metabolism, so you can increase fat burning and store less of it. These dietary supplements often utilize thermogenesis, which involves the body producing heat. The higher your internal temperature, the more your body utilizes and burns dietary fat.
Thermogenesis goes hand in hand with lipolysis, a process where the body breaks down fat. Lipolysis occurs in the tissue and fat deposits around the organs. Fat burners target any excess amount of fat and convert it into energy for the brain and body. For a list of the best weight loss supplements, check out Observer.
Carbohydrates come in two forms: simple and complex. Carb blockers target complex carbohydrates, which you can find in bread, pasta, and starchy foods. The drug prevents the body from breaking down the carbs so that they cannot contribute to your caloric intake.
Another benefit of carb blockers is their ability to bolster resistant starch levels in the intestines. The fewer carbohydrates you have for energy, the more starch remains in your gut. Resistant starch works like dietary fiber, allowing people to feel satiated for several hours.
Appetite suppressants give people control over their cravings and hunger pangs. The weight loss pills limit the number of hunger signals that go to the brain. Some prescription appetite suppressants include phentermine (Qsymia), naltrexone (Contrave), and liraglutide (Saxenda).
You can also find the best appetite suppressants in everyday foods and beverages, like green tea and coffee. The caffeine in these items reduces the desire to eat for a short period. Caffeine can also increase fat-burning and energy potential.
Do Weight Loss Supplements Have Any Side Effects?
All drugs, including thermogenic weight loss pills, have potential side effects. These risks vary based on the dosage, your health, and the amount of weight you want to lose. Some common side effects include:
Most of the side effects are minor and will disappear after a few days. Other side effects are more severe and can be precursors to addiction or abuse. If you experience long-term side effects, contact a medical professional for help.
Can Weight Loss Pills Help You Lose Fat Without Diet and Exercise?
Weight loss pills make it easier to burn fat and lose weight, but they can’t do it alone. A proper diet and regular exercise are the most effective ways to get rid of unwanted body fat. Dietary supplements are meant to work in tandem with this regimen.
You do not need to train like an Olympian or become a vegetarian to achieve weight loss. Try incorporating aerobic exercise into your routine three or four times a week. Some examples include cycling, jogging, swimming, basketball, and pilates. Healthy meals should feature an array of fruits and vegetables, with limited sugary treats and highly refined carbohydrates.
Can You Buy Weight Loss Products Over The Counter?
Yes, you can purchase over-the-counter weight loss pills. The problem is that they don’t contain the optimal mixture of active ingredients to achieve maximum weight loss. Alternatives, such as Leanbean and PhenQ, provide more reliable ways to lose weight and have fewer harsh side effects. Contrary to popular belief, the best-sellers for weight loss pills are actually found online.
How Much Weight Can I Lose With Diet Pills?
There are no hard and fast numbers when it comes to total pounds lost. Your final body weight will depend, in large part, on your current physique. Someone who weighs 300 pounds can shed significantly more body weight compared to someone who weighs 200 pounds.
Weight loss pill manufacturers say that you should see a 5% weight loss within the first three months. Your percentage may be higher or lower depending on your current weight. If you do not see 5% weight loss during that time, your doctor may recommend another medication.
How Fast Does It Take for a Weight Loss Supplement To Work?
Weight loss won’t happen overnight. If you stick to a consistent routine of physical activity and healthy eating, you may see results within the first two weeks. Remember that weight loss is a long-term goal, so it’s crucial to make gradual and sustainable changes.
Final Verdict – Are Weight Loss Pills Right for You?
Weight loss pills come in all shapes and sizes. The best choice is one that fits with your lifestyle and budget and doesn’t have lingering side effects. That way, you get the effective weight loss you want without breaking the bank.
Each supplement on our list comes with a unique formula and benefits. A supplement like Leanbean works best for women, while products like Instant Knockout cater to men with weight gain. Select your favorite brand and start achieving your weight loss goals today.