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Lipozene review: Effectiveness and safety

Lipozene is a popular diet pill for weight loss. It contains a soluble fiber called glucomannan that absorbs water to create a thick gel. This fiber may be responsible for many of the benefits of the supplement that people report.

Lipozene may have potential benefits in some cases. However, the weight loss effects are usually mild, and it is not right for everyone.

Diet pills, such as Lipozene, are not replacements for proven weight control methods, such as eating a healthful diet and exercising regularly.

In this article, we explore the safety of Lipozene, as well as its benefits, side effects, and effectiveness.

The soluble fiber glucomannan, the active ingredient in Lipozene, is safe when people use it as the manufacturers direct.

Importantly, the fiber absorbs many times its weight in water, so it is essential to stay hydrated.

This requirement means drinking plenty of fluids while using any products that contain konjac fiber.

The benefits of glucomannan, the active ingredient in Lipozene, relate to its specific type of soluble, fermentable, dietary fiber.

A review in the International Journal of Biological Macromolecules notes that glucomannan fiber may help:

  • reduce levels of glucose
  • reduce cholesterol
  • reduce fats in the blood
  • lower blood pressure
  • help enable weight loss

Many of these benefits come from how glucomannan behaves in the body. Glucomannan absorbs many times its weight in water, forming a gel-like substance that the digestive system processes with food.

May keep the body full

Taking Lipozene with a full glass of water before each meal creates a thick, gel-like substance in the stomach. This substance leaves less room in the stomach for food.

Because of this, a person who takes Lipozene may feel full sooner, which may reduce the chances of overeating.

May reduce calories from meals

As glucomannan can make the body feel fuller, it might reduce the calories a person eats with each meal. This could lead to weight loss over time if the person consumes fewer calories than they burn each day.

The fiber itself is also low in calories, so taking it does not add much to the diet.

May reduce caloric intake from other sources

Glucomannan may also help a person lose weight by reducing the energy they absorb. Soluble fibers, such as glucomannan, may reduce the absorption of nutrients, for example, fats.

This means the body might take up less energy from these food sources and, instead, pass these calories out with waste.

Source of prebiotic fiber

Glucomannan fiber is also prebiotic, meaning it feeds the healthy bacteria that colonize the intestines.

The Journal of Biological Macromolecules review notes that the stomach does not digest the fiber. Instead, the fiber passes through to the intestines where the intestinal bacteria can ferment it, and use it as fuel.

This process is important, as the health of the intestinal microorganisms influence the overall well-being of the body.

A study in Current Developments in Nutrition notes the benefits of prebiotic compounds, including their ability to:

  • increase healthy bacteria in the intestines
  • increase mineral absorption
  • decrease harmful bacteria in the gut
  • decrease allergy risk
  • cut harmful fermentation of proteins in the gut
  • improve the immune system response

While not every prebiotic fiber will act the same way, a diet rich in prebiotics may help ensure the intestinal flora are healthy.

Simple active ingredients

Another potential benefit is that Lipozene is a relatively simple form of weight loss supplement.

While some pills may contain stimulants, laxatives, or other additives, the only active ingredient in Lipozene is glucomannan.

For this reason, the product may be an option for people looking for more straightforward ingredients to help them with weight loss.

Most people tolerate glucomannan well. Some people may be more sensitive to soluble fibers, and mild reactions in the digestive system may occur.

Mild side effects from taking glucomannan may include:

  • stomach pain
  • gas
  • constipation
  • diarrhea

Some side effects may be worse if the person does not drink enough water along with the glucomannan, as the fiber is highly absorbent and may take water from the body.

Glucomannan may also reduce the absorption of certain medications. People can talk to a doctor before taking Lipozene to be sure it will not interact with any medications.


There is a risk of choking if an individual does not drink enough water along with Lipozene capsules.

If the capsules were to become stuck in the throat, they may expand and swell, blocking the esophagus.

People who have difficulty swallowing capsules may want to avoid Lipozene.

Anyone experiencing serious side effects, such as chest pain, difficulty breathing or swallowing after taking Lipozene must seek immediate medical attention.

Reactions from other ingredients

While glucomannan and konjac root are not common allergens, some people may be more sensitive to the added ingredients in Lipozene.

Aside from glucomannan from the konjac root, Lipozene capsules also contain:

  • gelatin
  • microcrystalline cellulose
  • magnesium silicate
  • stearic acid
  • titanium dioxide
  • FD&C Blue #1

Typically, the effectiveness of Lipozene for weight loss is mild. A review in Current Obesity Reports notes a broad body of research, including nine clinical trials, showing glucomannan may be mildly effective for weight loss.

The researchers note weight loss of between 0.5–1.7 pounds after taking glucomannan for 5.2 weeks.

However, an older 2013 study suggests that glucomannan does not promote weight loss, alter body composition, or change feelings of hunger or fullness.

For many, these mixed results may be enough to justify taking Lipozene to boost their diet and weight loss goals. Others may feel they do not justify the cost.

The Lipozene website recommends taking two capsules 30 minutes before each meal, along with a full glass of water, up to six capsules each day.

Dosage recommendation

A two-capsule serving of Lipozene contains 1,500 milligrams of konjac fiber. This serving should always include at least 8 ounces of water.

Taking glucomannan or Lizopene for weight loss appears to produce mild results in some cases. No dietary supplement is a replacement for other healthy weight loss habits.

Anyone looking to lose weight will still need to make changes to their diet and lifestyle. These changes often include eating a healthful diet, reducing caloric intake, and taking regular exercise.

Anyone worried about their weight should work with their doctor to create an individualized plan for weight loss.

Click here to learn how to lose weight fast naturally.

Lipozene is a well-reviewed dietary supplement. The active ingredient, glucomannan, is a natural fiber that may benefit the body when taken regularly with plenty of water.

No supplement will replace dietary and lifestyle changes for weight loss. Taking Lipozene may help support weight loss efforts for some people, though any additional weight loss resulting from the supplement is typically mild.

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