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Comprehensive Analysis of 250+ Key Companies Developing 250+ Novel CAR-T Therapies: DelveInsight

More than 50% of trials investigating CAR-T therapies for different indications are underway in the US, with around 80% of the trials for Haematological tumours.Los Angeles, USA, April 20, 2021 (GLOBE NEWSWIRE) — Comprehensive Analysis of 250+ Key Companies Developing 250+ Novel CAR-T Therapies: DelveInsight More than 50% of trials investigating CAR-T therapies for different indications are underway in the US, with around 80% of the trials for Haematological tumours. DelveInsight’s “CAR-T Pipeline Insight” report offers a broad view of available CAR-T therapies in the market, pipeline CAR-T therapies, their MoA, RoA, key companies working in the domain, and competitive assessment. The report analyzes over 60 molecules in Phase I/II, ~100 molecules in Phase I, ~150 molecules in Preclinical, and ~40 molecules in the Discovery stage for different indications. Some of the key takeaways from the CAR-T Pipeline Insights Report: The CAR-T therapy pipeline report offers an analysis of over 250 key companies and 250+ CAR-T therapies in different stages of clinical development. At present, more than 300 clinical trials of CAR-T cell therapies have been approved by several national drug regulatory agencies, including the US FDA. Key companies developing CAR-T therapies include AbbVie Inc., Adaptimmune Therapeutics PLC., Amgen, Inc., Atara Biotherapeutics, Inc., Aurora Biopharma, Inc., Autolus Therapeutics PLC., Bellicum Pharmaceuticals, Inc., BioAtla LLC., bluebird bio, Carina Biotech, CARsgen Therapeutics, Ltd., CARTherics, Celgene, Cellectis, Celularity, Celyad SA, Creative Biolabs, DiaCarta, Inc., Endocyte, Inc., F1 Oncology, Inc., Fate Therapeutics Inc., Gilead, Humanigen, Inc., Immune Therapeutics, Inc., Intrexon, Corp., Juno Therapeutics, Inc., Kite Pharma, Inc., Lion TCR Pte Ltd., MaxCyte, Inc., Mesoblast, Ltd., Minerva Biotechnologies Corp., Mustang Bio, Inc., Novartis AG, Oxford BioMedica PLC., PeproMene Bio Inc., Pfizer, Inc., Posedia Therapeutics Inc., Precision Biosciences, Inc., ProMab Biotechnologies Inc., Servier Oncology, Sorrento Therapeutics, Inc., TC Biopharm Ltd., Tessa Therapeutics Pte Ltd., TILT Biotherapeutics Ltd., Tmunity Therapeutics Inc., TrakCel Ltd., Xyphos, ZIOPHARM Oncology, Inc., and others.The companies with their CAR-T drug candidates in the most advanced stage, i.e. phase III include, Janssen Research & Development, ViiV Healthcare, Sorrento Therapeutics, Celgene, Novartis, and Abbott.Key CAR-T therapies in different stages of development include LCAR-B38M CAR-T Cell, Anti-CEA CAR-T cells, CD30.CAR-T, AUTO CAR T cell therapy, Defibrotide, MB-CART2019.1 Dose level 1, CAR-T, CD19/22 CART, JNJ-68284528, CD123 CAR-T cells, CD19 CAR-T cells, BCMA CAR-T cells, CEA CAR-T cells, CAR-T cell immunotherapy, Autologous CAR-T cells, Second generation CAR-T cells, CAR-T/TCR-T cells immunotherapy, Allogeneic hematological stem cell transplantation, Humanized CD19 CAR-T cells, CD19 CART, MB-CART20.1, MB-CART19.1, IM19 CAR-T Cells, CLDN6 CAR-T, Autologous CD19-targeting CAR T cells, P-BCMA-101 CAR-T cells, MLM-CAR44.1 T-cells, cyclophosphamide and fludarabine from -5 to -3, CART-19/22, Anakinra, Anti-MUC1 CAR-T cells, CAR T-cell therapy, CAR T cells, CART-19, CAR-CD19 T Cells, CAR-BCMA T Cells, LCAR-B38M CAR-T cell injection, AUTO1, AUTO3, Gene-modified (GM) T cell therapy, Descartes-08, iC9-CAR19 cells, ALLO-501A, and others. Interested in knowing more? Request for the sample @ CAR-T Cell Therapies Pipeline Analysis The report underlines the present unmet needs in the market, driving factors, and market constraints, along with the holistic view of the inactive therapeutics (comprising dormant and terminated products) with the reasons behind their downfall, detailed insights into the structure and gene editing tool of the pipeline CAR-T cell therapies to help clients gauge the opportunities and risks in the market. In the News In March 2021, Actinium Pharmaceuticals announced the initiation of patient enrolment in the Phase I study of Iomab-ACT for targeted conditioning before treatment with Memorial Sloan Kettering Cancer Center’s (MSK) CD19 targeted CAR T-cell 19-28z.In February 2021, AbbVie signed a collaboration and licensing agreement with Caribou Biosciences for the research and development of chimeric antigen receptor (CAR)-T cell therapeutics.In January 2021, Tessa Therapeutics announced that the European Medicines Agency (EMA) has granted PRiority MEdicines (PRIME) designation to the company’s lead autologous CD30 CAR-T therapy for the treatment of relapsed or refractory classical Hodgkin Lymphoma (R/R cHL). Interested in knowing more? Request for the sample @ CAR-T Pipeline Therapies At a Glance: Emerging CAR-T Therapies, RoA, MoA and Companies DrugCompanyClinical PhaseTarget IndicationRoAbb21217Bluebird Bio/ CelgenePhase IMultiple myelomaIntravenousUCART123CellectisPhase IAcute Myeloid Leukemia (AML)NADescartes-11Cartesian TherapeuticsPhase IIMultiple MyelomaNACTL119NovartisPhase IIAcute Lymphoid Leukemia, Multiple MyelomaInfusionAUTO5AutolusPreclinicalT-cell lymphomaNAAUTO3AutolusPhase I/IIDiffuse Large B Cell Lymphoma, Relapsed Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell LymphomaIntravenousCT053Carsgen TherapeuticsPhase I/IIMultiple MyelomaIntravenousCTL119NovartisPhase IIAcute Lymphoid Leukemia, Multiple MyelomaNATT11Tessa Therapeutics Phase IIHodgkin’s Lymphoma, Non-Hodgkin LymphomaInfusionMB-102Mustang BioPhase I/IIRelapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell NeoplasmIntravenousCEA CAR TSorrento TherapeuticsPhase II/IIIMalignant Tumor of Pancreas Metastatic to LiverIntrahepaticCNCT19CASI Pharmaceuticals/ Juventas Cell TherapyPhase IINon-Hodgkin’s Lymphoma, Relapsed or Refractory Acute Lymphoblastic Leukemia, Large B-cell Lymphoma, Relapsed or Refractory Hematological MalignanciesIntravenousDescartes-11Cartesian TherapeuticsPhase IIMultiple MyelomaNA Know more about budding CAR-T therapies projected to transform the landscape @ Emerging CAR-T Therapeutics and Market Scenario CAR-T Therapeutic Assessment The CAR-T Therapies Pipeline report proffers comprehensive insights into active pipeline assets segmented by Stage, Product Type, Route of Administration, Molecule Type, Target, and Indications of various drugs. By Product Type MonoCombination By Stage Discovery Pre-clinicalINDPhase IPhase IIPhase IIIPre-registration By Route of Administration IntrahepaticIntravenousIntratumoralIntraventricularIntraperitonealIntracavitaryParenteral By Mechanism of Action Anti-CEA CAR T-cell immunotherapyAnti-BCMA chimeric antigen receptor T-cell immunotherapyCD19-targeted chimeric antigen receptor T-cell immunotherapy By Targets CEABCMACD19 By Stage and Route of AdministrationBy Stage and Product Type To know more, Visit CAR-T Pipeline and Emerging Trends Scope of the report Coverage: GlobalKey Players: AbbVie Inc., Adaptimmune Therapeutics PLC., Amgen, Inc., Atara Biotherapeutics, Inc., Aurora Biopharma, Inc., Autolus Therapeutics PLC., Bellicum Pharmaceuticals, Inc., BioAtla LLC., bluebird bio, Carina Biotech, CARsgen Therapeutics, Ltd., CARTherics, Celgene, Cellectis, Celularity, Celyad SA, Creative Biolabs, DiaCarta, Inc., Endocyte, Inc., F1 Oncology, Inc., Fate Therapeutics Inc., Gilead, Humanigen, Inc., Immune Therapeutics, Inc., Intrexon, Corp., Juno Therapeutics, Inc., Kite Pharma, Inc., Lion TCR Pte Ltd., MaxCyte, Inc., Mesoblast, Ltd., Minerva Biotechnologies Corp., Mustang Bio, Inc., Novartis AG, Oxford BioMedica PLC., PeproMene Bio Inc., Pfizer, Inc., Posedia Therapeutics Inc., Precision Biosciences, Inc., ProMab Biotechnologies Inc., Servier Oncology, Sorrento Therapeutics, Inc., TC Biopharm Ltd., Tessa Therapeutics Pte Ltd., TILT Biotherapeutics Ltd., Tmunity Therapeutics Inc., TrakCel Ltd., Xyphos, ZIOPHARM Oncology, Inc., and others. Key CAR-T Pipeline Therapies: LCAR-B38M CAR-T Cell, Anti-CEA CAR-T cells, CD30.CAR-T, AUTO CAR T cell therapy, Defibrotide, MB-CART2019.1 Dose level 1, CAR-T, CD19/22 CART, JNJ-68284528, CD123 CAR-T cells, CD19 CAR-T cells, BCMA CAR-T cells, CEA CAR-T cells, CAR-T cell immunotherapy, Autologous CAR-T cells, Second generation CAR-T cells, CAR-T/TCR-T cells immunotherapy, Allogeneic hematological stem cell transplantation, Humanized CD19 CAR-T cells, CD19 CART, MB-CART20.1, MB-CART19.1, IM19 CAR-T Cells, CLDN6 CAR-T, Autologous CD19-targeting CAR T cells, P-BCMA-101 CAR-T cells, MLM-CAR44.1 T-cells, cyclophosphamide and fludarabine from -5 to -3, CART-19/22, Anakinra, Anti-MUC1 CAR-T cells, CAR T-cell therapy, CAR T cells, CART-19, CAR-CD19 T Cells, CAR-BCMA T Cells, LCAR-B38M CAR-T cell injection, AUTO1, AUTO3, Gene-modified (GM) T cell therapy, Descartes-08, iC9-CAR19 cells, ALLO-501A, and others. Want to learn more about the leading candidates in different clinical stages of trials? Reach out @ CAR-T Emerging Therapies and Key Companies Key Questions Answered in the Report How many companies are developing CAR-T drugs?How many CAR-T drugs are developed by each company?How many emerging drugs are in the mid-stage, and late-stage of development for the treatment of CAR-T?What are the key collaborations (Industry–Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the CAR-T therapeutics?What are the recent trends, drug types, and novel technologies developed to overcome the limitation of existing therapies?What are the clinical studies going on for CAR-T and their status?What are the key designations that have been granted to the emerging drugs? Got queries? Get in touch @ CAR-T Pipeline Therapies, and Clinical Trial Analysis Table of Contents 1Introduction2Executive Summary3CAR-T Therapies Overview4CAR-T Therapies Pipeline Scenario5CAR-T Therapies Pipeline Therapeutics6CAR-T Therapies Preclinical Stage Products7In-depth Commercial CAR-T Therapeutics Assessment8Late Stage CAR-T Pipeline Products (Phase III and Preregistration)9Mid-Stage CAR-T Pipeline Products (Phase II)10Pre-clinical and Discovery Stage CAR-T Pipeline Therapies 11Inactive CAR-T Pipeline Products12CAR-T Key Companies13CAR-T Key Products14Company-University Collaborations (Licensing/Partnering) Analysis15CAR-T Market Drivers and Barriers16CAR-T Future Perspectives and Conclusion17CAR-T Pipeline Therapies: Analyst Views18Appendix Know more about the report offerings @ CAR-T Therapies, and Upcoming Trends Related Reports CAR-T Cell Therapy For Acute Lymphoblastic Leukemia MarketDelveInsight’s “CAR T-Cell Therapy for Acute Lymphoblastic Leukemia (ALL)- Market Insights and Market Forecast- 2030” report. CAR-T Cell Therapy For Multiple Myeloma MarketDelveInsight’s ‘CAR T-Cell Therapy for Multiple Myeloma-Market Insights and Market Forecast-2030’ report. CAR-T Cell Therapy For Non-Hodgkin’s Lymphoma MarketDelveInsight’s ‘CAR T-Cell Therapy for Non-Hodgkin’s lymphoma (NHL) – Market Insights and Market Forecast-2030’ report. CAR-T Cell Immunotherapy Competitive Landscape Pipeline And Market Analysis“Chimeric Antigen Receptor T Cells – Competitive Landscape, Pipeline and Market Analysis, 2021” report. Adeno Associated Virus Vectors In Gene Therapy MarketDelveInsight’s “Adeno-Associated Virus Vectors in Gene Therapy – Market Insights, Epidemiology, and Market Forecast-2030” report. Gene Therapy In Oncology Innovation To Commercialization Competitive LandscapeDelveInsight “Gene Therapies in Oncology – Innovation to Commercialization: Competitive Landscape, Technological Advancements, Market Opportunities & Future Directions, 2018” report. Calcitonin Gene-Related Peptide Receptor Antagonist Pipeline InsightDelveInsight, “Calcitonin Gene-related Peptide Receptor (CGPR) Antagonists – Pipeline Insights, 2021” report. About DelveInsight DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing end-to-end comprehensive solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve. CONTACT: Contact Us Shruti Thakur info@delveinsight.com +1(919)321-6187 www.delveinsight.com



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